Keratoconus is a degenerative disorder of the eye in which structural changes within the cornea cause it to thin and change to a more conical shape than the more normal gradual curvature. The prevalence for keratoconus range from 1 in 500 to 1 in 2000 people.
Keratoconus can cause substantial distortion of vision, with multiple images, streaking and photophobia often reported by the patient. It is typically diagnosed in the patient’s adolescent years. If afflicting both eyes, the deterioration in vision can affect the patient’s ability to drive a car or read normal print.
Common Forms of Keratoconus
The corrective lenses during the first stages of the disease or contact lenses allow the patient to continue to drive legally and likewise function normally. Further progression of the disease may require surgery such as cross-linking (CXL) using riboflavin (vit B2) and UV light in order to avoid further progression leading to corneal transplantation. CXL can be combined with additional customized excimer laser treatment or intrastromal corneal ring segments in order to reshape the cornea.
Prof Kozobolis was the first to use cornea cross-linking (CXL) treating bullous keratopathy with or without corneal ulcer, a therapeutic approach which today is considered as standard therapeutic method for bullous keratopathy and corneal ulcer.
Additionally, he proved that this therapeutic approach (cornea cross-linking) has no influence in anterior chamber angle’s structure such as trabeculum and consequently to intraocular pressure (IOP) changes.